Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770871 | 0.76 | — | — | |
| SCHEMBL9767083 | 0.74 | HTT (0.50) | HTT | |
| SCHEMBL9767015 | 0.72 | HTT (0.51) | HTT | |
| SCHEMBL145648 | 0.69 | — | — | |
| SCHEMBL9766990 | 0.64 | HTT (0.43) | HTT | |
| SCHEMBL1067346 | 0.58 | HTT (0.45) | HTT | |
| SCHEMBL9685442 | 0.58 | HTT (0.38) | HTT | |
| SCHEMBL17911632 | 0.57 | KCNA3 (0.38) | — | |
| SCHEMBL2530176 | 0.57 | KCNA3 (0.50) | — | |
| SCHEMBL6470821 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072006-A | Chemical intermeidate; hypotensive agents, muscle relaxants | RECHERCHE SYNTEX FRANCE S.A. (FR) | 1991-12-10 | — | — | US | disclosed |
| US-4997846-A | Smooth muscle relaxants, hypotensives | RESEARCHE SYNTEX FRANCE, S.A. (FR) | 1991-03-05 | — | — | US | disclosed |
| EP-0377966-A2 | Novel benzopyranylpyrrolinone derivatives | RECHERCHE SYNTEX FRANCE SA (FR) | 1990-07-18 | — | — | EP | disclosed |