Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3740207 | 0.84 | ACHE (0.45) | ACHEHPGDMAPK1L3MBTL1KDM4E | |
| SCHEMBL4642722 | 0.81 | ACHE (0.52) | ACHECYP3A4TSHRHIF1AHPGD | |
| SCHEMBL2587092 | 0.78 | KDM4E (0.36) | ACHECYP3A4HPGDMAPK1L3MBTL1 | |
| SCHEMBL29054758 | 0.78 | KDM4E (0.58) | ACHEHPGDMAPK1CYP1A2SMN1; SMN2 | |
| SCHEMBL25863569 | 0.77 | ACHE (0.48) | ACHECYP3A4TSHRHIF1AHPGD | |
| SCHEMBL19465417 | 0.75 | TSHR (0.48) | ACHECYP3A4TSHRHIF1AHPGD | |
| SCHEMBL1370743 | 0.74 | ALOX5 (0.50) | ACHECYP3A4TSHRHIF1AHPGD | |
| SCHEMBL19529288 | 0.74 | ACHE (0.58) | ACHECYP3A4TSHRHIF1AHPGD | |
| SCHEMBL19275964 | 0.74 | IMPDH2 (0.55) | CYP3A4TSHRHIF1AHPGDHSD17B10 | |
| SCHEMBL27949633 | 0.74 | SENP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |