Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772077 | 0.85 | MAPT (0.37) | LMNAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL7380155 | 0.84 | ALDH1A1 (0.34) | LMNAALDH1A1MAPTMAPK1HTT | |
| SCHEMBL7771930 | 0.81 | SMN1; SMN2 (0.43) | RAB9ALMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL8118422 | 0.74 | ALDH1A1 (0.33) | LMNAALDH1A1MAPTMAPK1HTT | |
| SCHEMBL7773563 | 0.71 | SMN1; SMN2 (0.44) | LMNAKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL7214195 | 0.71 | ALDH1A1 (0.42) | RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL13120789 | 0.70 | HSPD1 (0.48) | KMT2AALDH1A1MEN1MAPTSMN1; SMN2 | |
| SCHEMBL8111245 | 0.69 | NPSR1 (0.41) | RAB9ALMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL7771927 | 0.69 | KDM4E (0.44) | RAB9ALMNAKMT2AALDH1A1NPC1 | |
| SCHEMBL7653556 | 0.68 | RAB9A (0.49) | RAB9ALMNAKMT2ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |