Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771637 | 0.91 | SMN1; SMN2 (0.41) | ALDH1A1MAPTPOLBHTTSMN1; SMN2 | |
| SCHEMBL7771919 | 0.88 | POLB (0.39) | ALDH1A1MAPTPOLBHTTSMN1; SMN2 | |
| SCHEMBL7771927 | 0.87 | KDM4E (0.44) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL7775674 | 0.85 | TP53 (0.48) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL7767875 | 0.85 | KDM4E (0.43) | ALDH1A1MAPTPOLBHTTTP53 | |
| SCHEMBL7771929 | 0.83 | SCN5A (0.40) | ALDH1A1MAPTPOLBTP53SMN1; SMN2 | |
| SCHEMBL7772064 | 0.82 | FPR1 (0.39) | ALDH1A1MAPTPOLBHTTSMN1; SMN2 | |
| SCHEMBL8107158 | 0.79 | IDH1 (0.39) | SMN1; SMN2 | |
| SCHEMBL7775637 | 0.75 | PTGDR2 (0.41) | ALDH1A1MAPTPOLBHTTSMN1; SMN2 | |
| SCHEMBL7773566 | 0.75 | MAPT (0.44) | ALDH1A1MAPTPOLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |