Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771919 | 0.87 | POLB (0.39) | SMN1; SMN2LMNAFPR1KMT2AMEN1 | |
| SCHEMBL7771927 | 0.86 | KDM4E (0.44) | TP53SMN1; SMN2LMNAHPGDFPR1 | |
| SCHEMBL7772080 | 0.85 | ALDH1A1 (0.38) | TP53SMN1; SMN2LMNAHPGDKMT2A | |
| SCHEMBL7771637 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2LMNAFPR1FPR2MAPT | |
| SCHEMBL7767875 | 0.84 | KDM4E (0.43) | TP53SMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL7772064 | 0.81 | FPR1 (0.39) | SMN1; SMN2HPGDFPR1FPR2KMT2A | |
| SCHEMBL7775637 | 0.75 | PTGDR2 (0.41) | SMN1; SMN2LMNAKMT2AMEN1MAPT | |
| SCHEMBL7773566 | 0.74 | MAPT (0.44) | SMN1; SMN2HPGDKMT2AMEN1MAPT | |
| SCHEMBL7767892 | 0.72 | POLB (0.39) | SMN1; SMN2LMNAHPGDKMT2AMEN1 | |
| SCHEMBL8107158 | 0.72 | IDH1 (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |