Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8125439 | 0.89 | FPR1 (0.39) | FPR1FPR2HTTIDH1KDM4E | |
| SCHEMBL7771927 | 0.85 | KDM4E (0.44) | FPR1FPR2POLBMAPTHTT | |
| SCHEMBL7771919 | 0.83 | POLB (0.39) | FPR1POLBMAPTHTTKDM4E | |
| SCHEMBL7772054 | 0.83 | FPR1 (0.41) | FPR1FPR2POLBHTTIDH1 | |
| SCHEMBL7772080 | 0.82 | ALDH1A1 (0.38) | POLBMAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7775674 | 0.81 | TP53 (0.48) | FPR1FPR2POLBMAPTHTT | |
| SCHEMBL7771637 | 0.81 | SMN1; SMN2 (0.41) | FPR1FPR2POLBMAPTHTT | |
| SCHEMBL7767875 | 0.81 | KDM4E (0.43) | POLBMAPTHTTIDH1KDM4E | |
| SCHEMBL7773566 | 0.75 | MAPT (0.44) | POLBMAPTHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7773577 | 0.74 | KAT2B (0.47) | FPR1FPR2POLBHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |