Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132225 | 0.92 | ALDH1A1 (0.46) | ALDH1A1HPGDCHUKDAPK3JAK2 | |
| SCHEMBL15396940 | 0.92 | ALDH1A1 (0.46) | ALDH1A1HPGDCHUKDAPK3JAK2 | |
| SCHEMBL7774230 | 0.87 | PSEN1 (0.50) | ALDH1A1HPGDPSEN1PSEN2APH1B | |
| SCHEMBL19870481 | 0.87 | PSEN1 (0.50) | ALDH1A1HPGDPSEN1PSEN2APH1B | |
| SCHEMBL1225200 | 0.87 | PSEN1 (0.50) | ALDH1A1HPGDPSEN1PSEN2APH1B | |
| SCHEMBL30775067 | 0.84 | PSEN1 (0.48) | ALDH1A1HPGDPSEN1PSEN2APH1B | |
| SCHEMBL7776149 | 0.81 | THRA (0.39) | ALDH1A1HPGDCHUKDAPK3JAK2 | |
| SCHEMBL23070366 | 0.80 | PSEN1 (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7777616 | 0.80 | PSEN1 (0.45) | ALDH1A1HPGDPSEN1PSEN2APH1B | |
| SCHEMBL31093433 | 0.77 | PSEN1 (0.43) | ALDH1A1HPGDPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704094-B1 | POLYMERS FOR OPTICAL DEVICES | CAMBRIDGE DISPLAY TECH LTD (GB) | 2001-08-08 | — | — | EP | disclosed |
| US-5514878-A | Polymers for electroluminescent devices | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |
| EP-0704094-A1 | POLYMERS FOR OPTICAL DEVICES | Cambridge Display Technology Limited (GB) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029883-A1 | POLYMERS FOR OPTICAL DEVICES | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |