SCHEMBL777426

SCHEMBL777426

Cc1cc(-c2ccccc2F)cc(-c2ccccc2F)c1C(=O)P(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTPRC P08575 1/20 0.38
PTPN1 P18031 1/20 0.38
ACMSD Q8TDX5 1/20 0.38
TNKS O95271 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
DHODH Q02127 9/20 0.36
DHFR P00374 1/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ERN1 O75460 1/20 0.36
NPC1 O15118 1/20 0.35
PKM P14618 1/20 0.35
RAB9A P51151 1/20 0.35
AKR1C4 P17516 1/20 0.34
AKR1C3 P42330 1/20 0.34
CTSA P10619 1/20 0.34
GRM2 Q14416 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL779346 0.82 GRM2 (0.39) ALDH1A1MAPTL3MBTL1ACMSDDHODH
SCHEMBL3893674 0.78 PTPRC (0.41) ALDH1A1MAPTL3MBTL1PTPRCPTPN1
SCHEMBL777427 0.77 MAPT (0.34) ALDH1A1MAPTL3MBTL1NPSR1GRM2
SCHEMBL779347 0.70 MYC (0.38) ALDH1A1MAPTL3MBTL1ACMSDDHODH
SCHEMBL10024266 0.66 ACMSD (0.65) ALDH1A1MAPTL3MBTL1PTPRCPTPN1
SCHEMBL3883387 0.65 GRM2 (0.39) ALDH1A1MAPTL3MBTL1PTPRCPTPN1
SCHEMBL27900617 0.65 ACMSD (0.64) ALDH1A1ACMSDDHODHDHFRALKBH5
SCHEMBL29883839 0.65 ALDH1A1 (0.37) ALDH1A1MAPTNPSR1NPC1RAB9A
SCHEMBL28232231 0.65 ALDH1A1 (0.37) ALDH1A1MAPTNPSR1NPC1RAB9A
SCHEMBL28116695 0.65 PTPRC (0.54) ALDH1A1MAPTL3MBTL1PTPRCPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed