SCHEMBL7774666

SCHEMBL7774666

C=CSCCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.45
CYP2D6 P10635 3/20 0.45
CYP2C19 P33261 3/20 0.45
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
CYP2A6 P11509 1/20 0.42
HTR2A P28223 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
NOS1 P29475 2/20 0.42
IDO1 P14902 1/20 0.40
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10978323 0.87 MAOA (0.47) HTR2ANOS1IDO1MAOBMAOA
SCHEMBL10980336 0.86 SIGMAR1 (0.47) IDO1MAOBMAOA
SCHEMBL27840281 0.80 LOXL2 (0.41) CYP1A2CYP2D6CYP2C19CYP2A6HTR2A
SCHEMBL2723228 0.78 MAOB (0.46) CYP1A2CYP2D6CYP2C19ALDH1A1HSD17B10
SCHEMBL8722949 0.76 CYP1A2 (0.45) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL21233204 0.76 SIGMAR1 (0.48) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL24524846 0.73 TSHR (0.47) TDP1SMN1; SMN2CA2
SCHEMBL11380502 0.73 TP53 (0.42) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL13138373 0.73 CYP1A2 (0.52) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD
SCHEMBL273439 0.72 CYP1A2 (0.50) CYP1A2CYP2D6CYP2C19ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711813-B1 Antifouling coating composition HITACHI CHEMICAL CO LTD (JP) 2001-07-25 EP disclosed
US-5773508-A BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS HITACHI CHEMICAL COMPANY, LTD. (JP) 1998-06-30 US disclosed
EP-0711813-A2 Coating varnish composition and antifouling coating composition Hitachi Chemical Co., Ltd. (JP) 1996-05-15 EP disclosed
US-4029706-A Reduction with polymeric reagent DYNAPOL (US) 1977-06-14 US disclosed
US-4000201-A ALKYL ETHER, CROSSLINKED SULFIDE POLYMER DYNAPOL CORPORATION (US) 1976-12-28 US disclosed
US-3995094-A BY REACTION WITH A HALOMETHOXYBUTANE DYNAPOL CORPORATION (US) 1976-11-30 US disclosed