Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774763 | 0.83 | TSHR (0.53) | TSHRHPGDATMNAAAALDH1A1 | |
| SCHEMBL3364135 | 0.82 | ATM (0.50) | TSHRHPGDATMNAAAALDH1A1 | |
| SCHEMBL7767047 | 0.81 | DGKA (0.53) | TSHRHPGDATMNAAAALDH1A1 | |
| SCHEMBL20261873 | 0.80 | TSHR (0.50) | TSHRHPGDATMNAAAALDH1A1 | |
| SCHEMBL7770911 | 0.79 | — | — | |
| SCHEMBL195751 | 0.79 | ALDH1A1 (0.54) | TSHRHPGDATMNAAAALDH1A1 | |
| SCHEMBL1656040 | 0.79 | TSHR (0.75) | TSHRHPGDATMNAAAALDH1A1 | |
| SCHEMBL7767124 | 0.78 | TSHR (0.52) | TSHRHPGDATMNAAAALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28863008 | 0.78 | ALDH1A1 (0.52) | TSHRHPGDATMNAAAALDH1A1 | |
| SCHEMBL21275447 | 0.77 | ALDH1A1 (0.56) | TSHRHPGDATMNAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020245229-A1 | ACETAL-BASED CLEAVABLE LINKERS | SYNAFFIX B.V. (NL) | 2020-12-10 | — | — | WO | disclosed |
| EP-0711813-B1 | Antifouling coating composition | HITACHI CHEMICAL CO LTD (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-5773508-A | BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0711813-A2 | Coating varnish composition and antifouling coating composition | Hitachi Chemical Co., Ltd. (JP) | 1996-05-15 | — | — | EP | disclosed |