SCHEMBL7775101

SCHEMBL7775101

CON=C(C(=O)OC)c1ccc2ccccc2c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.51
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
KDM4A O75164 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
KDM4C Q9H3R0 1/20 0.46
GAA P10253 3/20 0.45
HIF1A Q16665 2/20 0.45
ABCG2 Q9UNQ0 2/20 0.45
CYP1A1 P04798 1/20 0.45
CYP1B1 Q16678 1/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
ALDH1A1 P00352 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
POLB P06746 1/20 0.44
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776559 0.80 LDHA (0.59) LDHAKMT2AMEN1KDM4ACTDSP1
SCHEMBL244541 0.77 LDHA (0.62) LDHAKMT2AMEN1KDM4ACTDSP1
SCHEMBL6705433 0.75 LMNA (0.55) GAAHIF1AKDM4EMAPTALDH1A1
SCHEMBL6705432 0.75 LMNA (0.55) GAAHIF1AKDM4EMAPTALDH1A1
SCHEMBL7119395 0.75 LMNA (0.55) GAAHIF1AKDM4EMAPTALDH1A1
SCHEMBL9656178 0.74 HIF1A (0.48) KMT2AMEN1HIF1AKDM4EMAPT
SCHEMBL8617535 0.72 HIF1A (0.52) KMT2AHIF1AKDM4EALDH1A1HTT
SCHEMBL7040691 0.72 HIF1A (0.51) KMT2AMEN1HIF1ALMNAPOLB
SCHEMBL6155893 0.72 HIF1A (0.51) KMT2AMEN1HIF1ALMNAPOLB
SCHEMBL29810082 0.72 HIF1A (0.51) KMT2AMEN1HIF1ALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0385357-B1 ORTHO-SUBSTITUTED 1-NAPHTHYL ETHERS, AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1992-04-29 EP claimed
EP-0385357-A1 Ortho-substituted 1-naphthyl ethers, and fungicides containing them BASF Aktiengesellschaft (DE) 1990-09-05 EP claimed
EP-0647631-B1 Naphthylether, processes for their use, agents containing them and their use as fungicides BASF AG (DE) 2001-08-16 EP disclosed
US-5602181-A PESTICIDES, FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-02-11 US disclosed
EP-0647631-A1 Naphthylether, processes for their use, agents containing them and their use as fungicides BASF Aktiengesellschaft (DE) 1995-04-12 EP disclosed
EP-0385357-B1 ORTHO-SUBSTITUTED 1-NAPHTHYL ETHERS, AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1992-04-29 EP disclosed
US-5057537-A Use on foilage, soils BASF AKTIENGESELLSCHAFT (DE) 1991-10-15 US disclosed
EP-0385357-A1 Ortho-substituted 1-naphthyl ethers, and fungicides containing them BASF Aktiengesellschaft (DE) 1990-09-05 EP disclosed