SCHEMBL9656178

SCHEMBL9656178

CON=C(C(=O)OC)c1ccc2ccccc2c1OCc1ccccc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.48
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
PRMT5 O14744 1/20 0.41
WDR77 Q9BQA1 1/20 0.41
PARP15 Q460N3 1/20 0.40
PARP10 Q53GL7 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7775101 0.74 LDHA (0.51) HIF1AMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL9019947 0.73 HIF1A (0.67) HIF1APARP15PARP10MAOB
SCHEMBL8370532 0.72 HIF1A (0.45) HIF1AMEN1KMT2ASMN1; SMN2HDAC3
SCHEMBL9415813 0.72 HIF1A (0.45) HIF1AMEN1KMT2ASMN1; SMN2HDAC3
SCHEMBL7775118 0.71 HIF1A (0.39) HIF1AMEN1KMT2AKDM4EHDAC3
SCHEMBL13823672 0.70 HIF1A (0.61) HIF1AKDM4E
SCHEMBL9025823 0.69 HIF1A (0.80) HIF1AKDM4ESMN1; SMN2
SCHEMBL6571845 0.69 HIF1A (0.80) HIF1AKDM4ESMN1; SMN2
SCHEMBL23971813 0.69 HIF1A (0.56) HIF1AKMT2AKDM4ESMN1; SMN2
SCHEMBL8370572 0.69 HIF1A (0.52) HIF1AMEN1KMT2AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0385357-B1 ORTHO-SUBSTITUTED 1-NAPHTHYL ETHERS, AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1992-04-29 EP disclosed
US-5057537-A Use on foilage, soils BASF AKTIENGESELLSCHAFT (DE) 1991-10-15 US disclosed