Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980413 | 0.96 | CTSC (0.55) | CTSCHTR2CHTR2BCYP3A4CYP2D6 | |
| SCHEMBL30051143 | 0.82 | CTSC (0.59) | CTSCHTR2CHTR2BCYP3A4CYP2D6 | |
| SCHEMBL1980119 | 0.82 | DPP4 (0.45) | CTSCKDM4E | |
| SCHEMBL1978322 | 0.81 | FKBP1A (0.47) | — | |
| SCHEMBL10709444 | 0.81 | MEN1 (0.60) | CTSCHTR2CHTR2BEPHX1 | |
| SCHEMBL10706722 | 0.81 | MEN1 (0.60) | CTSCHTR2CHTR2BEPHX1 | |
| SCHEMBL1981342 | 0.81 | GHSR (0.47) | CTSCCYP2C19GHSRTSHREPHX1 | |
| SCHEMBL1978336 | 0.80 | ITGB3 (0.47) | CYP3A4CYP2D6TSHRKDM4E | |
| SCHEMBL9283152 | 0.80 | CTSC (0.65) | CTSCHTR2CHTR2BCYP3A4CYP2D6 | |
| SCHEMBL1980094 | 0.80 | GHSR (0.45) | CYP2C19GHSRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117372-A2 | METHOD OF TREATING HAIR LOSS USING SULFONAMIDES | THE PROCTER & GAMBLE COMPANY (US) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000018361-A2 | METHOD OF TREATING HAIR LOSS USING SULFONAMIDES | THE PROCTER & GAMBLE COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |