Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780890 | 0.91 | CTRB1 (0.46) | CTRB1CTSKCTSLSMN1; SMN2CYP1A2 | |
| SCHEMBL7775756 | 0.90 | CTRB1 (0.46) | CTRB1CTSKCTSLSMN1; SMN2CYP1A2 | |
| SCHEMBL7780914 | 0.90 | CTSL (0.44) | CTRB1CTSKCTSLSMN1; SMN2CTSB | |
| SCHEMBL7775452 | 0.80 | CTRB1 (0.52) | CTRB1CTSKCTSLSMN1; SMN2CYP1A2 | |
| SCHEMBL7782326 | 0.80 | CTRB1 (0.52) | CTRB1CTSKSMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7455452 | 0.78 | CTRB1 (0.54) | CTRB1CTSKCTSLSMN1; SMN2CYP1A2 | |
| SCHEMBL7780900 | 0.78 | CTRB1 (0.54) | CTRB1CTSKCTSLSMN1; SMN2CYP1A2 | |
| SCHEMBL7455442 | 0.78 | CTRB1 (0.54) | CTRB1CTSKCTSLSMN1; SMN2CYP1A2 | |
| SCHEMBL7782474 | 0.77 | SGMS2 (0.54) | CTRB1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL8717314 | 0.76 | CTRB1 (0.52) | CTRB1MEN1KMT2ACTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815074-B1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | SK CORP (KR) | 2001-10-04 | — | — | EP | disclosed |
| US-5756817-A | TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEMS | YUKONG LIMITED (KR) | 1998-05-26 | — | — | US | disclosed |
| US-5705640-A | O-carbamoyl-(d)-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same | YUKONG LIMITED (KR) | 1998-01-06 | — | — | US | disclosed |
| WO-1996024577-A1 | O-CARBAMOYL-(D)-PHENYLALANILOL COMPOUNDS AND PROCESS FOR PREPARING THE SAME | YUKONG LIMITED (KR) | 1996-08-15 | — | — | WO | disclosed |