Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11698202 | 0.71 | LTA4H (0.40) | LTA4HSMN1; SMN2ABCB1SLC15A1ALDH1A1 | |
| SCHEMBL11696239 | 0.67 | LTA4H (0.37) | LTA4HSMN1; SMN2ABCB1SLC15A1CASP1 | |
| SCHEMBL7775661 | 0.66 | LTA4H (0.33) | LTA4HSMN1; SMN2ABCB1SLC15A1CTSL | |
| SCHEMBL8346336 | 0.66 | CHRM2 (0.36) | LTA4HSMN1; SMN2ABCB1SLC15A1CTSL | |
| SCHEMBL11280290 | 0.65 | SLC15A1 (0.43) | LTA4HSMN1; SMN2SLC15A1ALDH1A1 | |
| SCHEMBL10901317 | 0.65 | SLC15A1 (0.43) | LTA4HSMN1; SMN2SLC15A1ALDH1A1 | |
| SCHEMBL8342232 | 0.65 | S1PR1 (0.39) | LTA4HSMN1; SMN2ALDH1A1 | |
| SCHEMBL169622 | 0.64 | LTA4H (0.54) | LTA4HSMN1; SMN2SLC15A1ALDH1A1 | |
| SCHEMBL27873595 | 0.64 | LTA4H (0.54) | LTA4HSMN1; SMN2SLC15A1ALDH1A1 | |
| SCHEMBL304415 | 0.64 | LTA4H (0.54) | LTA4HSMN1; SMN2SLC15A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837877-B1 | L-ASPARTYL-L-THIENYLALANINE METHYL ESTERS, PROCESS FOR PRODUCING THEM AND THEIR USE AS SWEETENERS | PHARMACON FORSCHUNG & BERATUNG GMBH (AT) | 2001-08-16 | — | — | EP | disclosed |
| US-5929253-A | L-aspartyl-L-thienylalanine methyl ester, process for its preparation and use as sweetener | PHARMACON FORSCHUNG UND BERATUNG GMBH (AT) | 1999-07-27 | — | — | US | disclosed |