Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775661 | 0.85 | LTA4H (0.33) | CHRM2CHRM1CHRM3LTA4HSMN1; SMN2 | |
| SCHEMBL26330374 | 0.76 | ALDH1A1 (0.44) | CHRM2CHRM1CHRM3SMN1; SMN2KMT2A | |
| SCHEMBL9301990 | 0.72 | ABCB1 (0.40) | LTA4HSMN1; SMN2KMT2ASLC15A1ABCB1 | |
| SCHEMBL10610709 | 0.71 | LTA4H (0.38) | LTA4HSMN1; SMN2KMT2ASLC15A1ABCB1 | |
| SCHEMBL11698202 | 0.67 | LTA4H (0.40) | LTA4HSMN1; SMN2KMT2ASLC15A1ABCB1 | |
| SCHEMBL7825113 | 0.67 | CHRM2 (0.43) | CHRM2CHRM1CHRM3KMT2ASLC15A1 | |
| SCHEMBL7826559 | 0.67 | CHRM2 (0.43) | CHRM2CHRM1CHRM3KMT2ASLC15A1 | |
| SCHEMBL7541791 | 0.67 | L3MBTL1 (0.39) | CHRM2CHRM1CHRM3LTA4HSMN1; SMN2 | |
| SCHEMBL7775655 | 0.66 | LTA4H (0.33) | LTA4HSMN1; SMN2SLC15A1ABCB1CTSL | |
| SCHEMBL7827377 | 0.66 | SMN1; SMN2 (0.38) | CHRM2CHRM1CHRM3SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929253-A | L-aspartyl-L-thienylalanine methyl ester, process for its preparation and use as sweetener | PHARMACON FORSCHUNG UND BERATUNG GMBH (AT) | 1999-07-27 | — | — | US | disclosed |