SCHEMBL7775745

SCHEMBL7775745

CCC(=O)c1cc(Cc2cc(C(=O)CC)c(O)c(O)c2O)c(O)c(O)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AB1 P08238 1/20 0.44
HMGCR P04035 1/20 0.42
BCL2 P10415 2/20 0.41
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
UBE2N P61088 1/20 0.40
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
PTGS1 P23219 1/20 0.39
DRD3 P35462 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
POLB P06746 1/20 0.38
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
HMGB1 P09429 1/20 0.37
CXCL12 P48061 1/20 0.37
PTPN2 P17706 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15314345 0.85 BCL2 (0.61) BCL2PPARGPPARAPTPN2PTPN1
SCHEMBL7773855 0.85 ALDH1A1 (0.52) HMGCRBCL2HSD17B10ALDH1A1HPGD
SCHEMBL7773975 0.80 HTT (0.51) HSD17B10KDM4EMAPTMEN1KMT2A
SCHEMBL3657409 0.79 MEN1 (0.47) BCL2HSD17B10KDM4EMAPTMEN1
SCHEMBL9468226 0.79 PLA2G2A (0.53) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL7773832 0.79 PLA2G2A (0.53) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL7773963 0.79 PLA2G2A (0.53) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL7775778 0.79 PLA2G2A (0.53) KDM4EMAPTMEN1KMT2AALDH1A1
SCHEMBL27589936 0.74 MEN1 (0.56) HSP90AB1HMGCRHSD17B10KDM4EMAPT
SCHEMBL15314352 0.73 BCL2 (0.54) HSP90AB1HMGCRBCL2MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445819-B1 Positive type photoresist composition FUJI PHOTO FILM CO LTD (JP) 2001-08-22 EP disclosed
EP-0488686-B1 A process of making naphthoquinone diazide esters using lactone solvents HOECHST CELANESE CORP (US) 1995-09-27 EP disclosed
EP-0508269-B1 Radiation-sensitive ester and process for its production HOECHST AG (DE) 1995-02-01 EP disclosed
EP-0369219-B1 Light-sensitive compounds, preparation of a light-sensitive mixture therewith and a recording material HOECHST AG (DE) 1995-01-04 EP disclosed
US-5300396-A Process of making naphthoquinone diazide esters using lactone solvents HOECHST CELANESE CORPORATION (US) 1994-04-05 US disclosed
US-5268252-A Polyol with o-naphthoquinone-2-diazide-4-sulfonic acid HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-07 US disclosed
US-5256522-A Image reversal negative working O-naphthoquinone diazide and cross-linking compound containing photoresist process with thermal curing HOECHST CELANESE CORPORATION (US) 1993-10-26 US disclosed
EP-0244763-B1 POSITIVE-WORKING PHOTOSENSITIVE COMPOSITION AND PHOTOSENSITIVE RECORDING MATERIAL PREPARED THEREFROM HOECHST CELANESE CORPORATION (US) 1993-03-10 EP disclosed
US-5162510-A Prepared by condensing phenolic compounds with a 1,2-naphthoquinonediazide-4-sulfonic acid halide and an organic acid halide HOECHST CELANESE CORPORATION (US) 1992-11-10 US disclosed
EP-0508269-A1 Radiation-sensitive ester and process for its production HOECHST AKTIENGESELLSCHAFT (DE) 1992-10-14 EP disclosed
US-4863827-A O-QUINONE DIAZIDE AMERICAN HOECHST CORPORATION (US) 1989-09-05 US disclosed
EP-0264845-A2 Multilayer positive-registration material HOECHST CELANESE CORPORATION (US) 1988-04-27 EP disclosed
US-4732836-A SOLUTION STABILITY PHENOLIC COMPOUNDS CONDENSED WITH QUINONES HOECHST CELANESE CORPORATION (US) 1988-03-22 US disclosed
US-4732837-A Novel mixed ester O-quinone photosensitizers HOECHST CELANESE CORPORATION (US) 1988-03-22 US disclosed
EP-0244763-A2 Positive-working photosensitive composition and photosensitive recording material prepared therefrom HOECHST CELANESE CORPORATION (US) 1987-11-11 EP disclosed
EP-0244762-A2 Photosensitive positive composition and photosensitive registration material prepared therefrom HOECHST CELANESE CORPORATION (US) 1987-11-11 EP disclosed
EP-0243964-A2 Photosensitive positive composition and photosensitive registration material prepared therefrom HOECHST CELANESE CORPORATION (US) 1987-11-04 EP disclosed
EP-0052788-B1 PHOTOSENSITIVE MIXTURE BASED ON O-NAPHTHOQUINONE DIAZIDES, AND PHOTOSENSIBLE COPYING MATERIAL MADE THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1984-08-01 EP disclosed
US-4407926-A PHOTORESISTS, PRINTING PLATES HOECHST AKTIENGESELLSCHAFT (DE) 1983-10-04 US disclosed
EP-0052788-A1 Photosensitive mixture based on o-naphthoquinone diazides, and photosensible copying material made therefrom HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-02 EP disclosed