Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628437 | 0.84 | IDO1 (0.43) | ALDH1A1IDO1MEN1KMT2AMAPT | |
| SCHEMBL10628642 | 0.81 | TLR8 (0.43) | ALDH1A1MAPTHTTPOLBRAB9A | |
| SCHEMBL1506754 | 0.80 | L3MBTL1 (0.43) | ALDH1A1MAPTHTTNPC1RAB9A | |
| SCHEMBL19707177 | 0.79 | IDO1 (0.40) | ALDH1A1IDO1MEN1KMT2AUSP2 | |
| SCHEMBL5535602 | 0.79 | KMT2A (0.48) | ALDH1A1IDO1MEN1KMT2AUSP2 | |
| SCHEMBL472991 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL11281857 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTHTTTSHRP2RX7 | |
| SCHEMBL24968636 | 0.79 | IDO1 (0.41) | IDO1MEN1KMT2AUSP2CASP1 | |
| SCHEMBL23248725 | 0.78 | L3MBTL1 (0.45) | SMN1; SMN2LMNAP2RX7L3MBTL1 | |
| SCHEMBL10623845 | 0.78 | L3MBTL1 (0.45) | SMN1; SMN2LMNAP2RX7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230128639-A1 | PROCESS FOR PREPARING SOLUBLE GUANYLATE CYCLASE STIMULATORS | TISENTO THERAPEUTICS INC. | 2023-04-27 | — | — | US | disclosed |
| US-20210032254-A1 | PROCESS FOR PREPARING SOLUBLE GUANYLATE CYCLASE STIMULATORS | TISENTO THERAPEUTICS INC. | 2021-02-04 | — | — | US | disclosed |
| US-10844064-B2 | sGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| EP-3680236-A1 | AROMATIC DERIVATIVE, PREPARATION METHOD FOR SAME, AND MEDICAL APPLICATIONS THEREOF | Bioardis LLC (US) | 2020-07-15 | — | — | EP | disclosed |
| US-10639308-B2 | sGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2020-05-05 | — | — | US | disclosed |
| US-10618878-B1 | Catalytic reduction of aromatic ring in aqueous medium | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2020-04-14 | — | — | US | disclosed |
| US-10472363-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190167679-A1 | sGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2019-06-06 | — | — | US | disclosed |
| US-20180155345-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-06-07 | — | — | US | disclosed |
| US-20180065971-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2018-03-08 | — | — | US | disclosed |
| EP-1699455-B1 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2013-05-08 | — | — | EP | disclosed |
| EP-1744212-A2 | Photosensitive composition | Fuji Photo Film Co., Ltd. (JP) | 2007-01-17 | — | — | EP | disclosed |
| EP-1119660-A1 | CELLULOSIC SUPPORT TREATMENT | MORGAN ADHESIVES COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2001004418-A1 | CELLULOSIC SUPPORT TREATMENT | MORGAN ADHESIVES COMPANY (US) | 2001-01-18 | — | — | WO | disclosed |
| EP-0859284-A1 | Water-developable photosensitive composition and production process thereof | Nippon Paint Co., Ltd. (JP) | 1998-08-19 | — | — | EP | disclosed |
| US-5506275-A | RESISTANCE TO ABRASION AND CRACKING ON FLEX | BASF CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |
| US-5180799-A | Organolithium-Organoaluminum Catalyst | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-19 | — | — | US | disclosed |
| EP-0434316-A1 | Processes | ZENECA LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |
| US-4734351-A | DISPERSION OF POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0091039-B1 | ANTI-FOULING AGENT | Nitto Kasei Co., Ltd. (JP) | 1986-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10618878-B1 | Catalytic reduction of aromatic ring in aqueous medium | TYR, SUB1, AHR | ALDH1A1 2125/4885IDO1 56/4885MEN1 3485/4885 |
| US-10472363-B2 | SGC stimulators | GUCY1A2, PRKG1, GMPS | ALDH1A1 2650/4885IDO1 3944/4885MEN1 4282/4885 |
| US-20210032254-A1 | PROCESS FOR PREPARING SOLUBLE GUANYLATE CYCLASE STIMULATORS | GUCY1A2, GUCY1B2, GUCY1A1 | ALDH1A1 3061/4885IDO1 4149/4885MEN1 2645/4885 |
| US-20230128639-A1 | PROCESS FOR PREPARING SOLUBLE GUANYLATE CYCLASE STIMULATORS | GUCY1A2, GUCY1B2, GUCY1A1 | ALDH1A1 3061/4885IDO1 4149/4885MEN1 2645/4885 |
| US-10639308-B2 | sGC stimulators | PTGIS, CGAS, GUCY1A1 | ALDH1A1 1529/4885IDO1 2665/4885MEN1 2447/4885 |
| US-20180065971-A1 | sGC STIMULATORS | GUCY1A2, PRKG1, GMPS | ALDH1A1 2650/4885IDO1 3944/4885MEN1 4282/4885 |
| US-10844064-B2 | sGC stimulators | GUCY1B1, GUCY1A1, PRKG1 | ALDH1A1 1902/4885IDO1 4120/4885MEN1 3638/4885 |
| US-20190167679-A1 | sGC STIMULATORS | PTGIS, CGAS, GUCY1A1 | ALDH1A1 1529/4885IDO1 2665/4885MEN1 2447/4885 |
| US-20180155345-A1 | sGC STIMULATORS | GUCY1B1, GUCY1A1, PRKG1 | ALDH1A1 1902/4885IDO1 4120/4885MEN1 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.