Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.69 |
| ▸ | BCHE | P06276 | 4/20 | 0.69 |
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 3/20 | 0.64 |
| ▸ | DRD4 | P21917 | 2/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776278 | 0.94 | ACHE (0.72) | ACHEBCHEMAOBDRD2DRD4 | |
| SCHEMBL20656948 | 0.85 | BCHE (0.70) | ACHEBCHEMAOBDRD2DRD4 | |
| SCHEMBL28437119 | 0.83 | BCHE (0.68) | ACHEBCHEMAOBDRD2DRD4 | |
| SCHEMBL8549859 | 0.82 | DRD2 (0.85) | ACHEBCHEMAOBDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8555532 | 0.81 | DRD2 (0.83) | ACHEBCHEMAOBDRD2DRD4 | |
| SCHEMBL1317607 | 0.80 | BCHE (0.70) | ACHEBCHEMAOBDRD2DRD4 | |
| SCHEMBL8059465 | 0.79 | LMNA (0.46) | ACHEBCHEMAOB | |
| Hydrochloric Acid SCHEMBL1314603 | 0.79 | BCHE (0.69) | ACHEBCHEMAOBDRD2DRD4 | |
| SCHEMBL10740997 | 0.78 | BCHE (0.56) | ACHEBCHEMAOBDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7777099 | 0.78 | SIGMAR1 (0.60) | ACHEBCHEMAOBDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129073-A2 | PROCESS AND INTERMEDIATES FOR PRODUCTION OF DONEPEZIL AND RELATED COMPOUNDS | Finetech Ltd (IL) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000009483-A2 | PROCESS AND INTERMEDIATES FOR PRODUCTION OF DONEPEZIL AND RELATED COMPOUNDS | FINETECH LTD. (IL) | 2000-02-24 | — | — | WO | disclosed |