P-Nitrophenol

P-Nitrophenol

SCHEMBL7776372

Cc1ccc(S(=O)(=O)N[C@@H](C)C(=O)O)cc1.O=[N+]([O-])c1ccc(O)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP9 P14780 5/20 0.57
MMP2 P08253 4/20 0.57
MMP1 P03956 3/20 0.57
MMP3 P08254 3/20 0.57
MMP7 P09237 3/20 0.57
MMP13 P45452 3/20 0.57
SLC1A3 P43003 2/20 0.53
SLC1A2 P43004 2/20 0.53
SLC1A1 P43005 2/20 0.53
ADAMTS4 O75173 2/20 0.52
MAPT P10636 3/20 0.49
ALDH1A1 P00352 2/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
CYTH2 Q99418 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
KMT2A Q03164 1/20 0.48
CA12 O43570 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5193258 0.89 MMP2 (0.68) MMP9MMP2MMP1MMP3MMP7
SCHEMBL22492652 0.89 MMP2 (0.68) MMP9MMP2MMP1MMP3MMP7
SCHEMBL4975578 0.84 ADAMTS4 (0.71) MMP9MMP2MMP1MMP3MMP7
SCHEMBL698908 0.84 ADAMTS4 (0.71) MMP9MMP2MMP1MMP3MMP7
SCHEMBL698907 0.84 ADAMTS4 (0.71) MMP9MMP2MMP1MMP3MMP7
Water SCHEMBL29881522 0.82 ADAMTS4 (0.69) MMP9MMP2MMP1MMP3MMP7
SCHEMBL9706817 0.79 HTT (0.65) MMP9MMP2MMP1MMP3MMP7
SCHEMBL7776370 0.79 HTT (0.65) MMP9MMP2MMP1MMP3MMP7
SCHEMBL8141494 0.77 TDP1 (0.72) MMP9MMP2MMP1MMP3MMP7
SCHEMBL8141491 0.77 TDP1 (0.72) MMP9MMP2MMP1MMP3MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0713093-B1 Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid BAYER AG (US) 2001-10-10 EP disclosed
US-5663044-A Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid BAYER CORPORATION (US) 1997-09-02 US disclosed
EP-0713093-A2 Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid Bayer Corporation (US) 1996-05-22 EP disclosed