Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776370 | 1.00 | HTT (0.65) | HTTMAPTRAB9ANPC1KMT2A | |
| SCHEMBL19404003 | 0.90 | HTT (0.54) | HTTMAPTRAB9ANPC1MMP2 | |
| SCHEMBL24211175 | 0.85 | HSD17B10 (0.50) | HTTMAPTRAB9ANPC1KMT2A | |
| SCHEMBL9764157 | 0.84 | HTT (0.49) | HTTMAPTRAB9ANPC1KMT2A | |
| SCHEMBL10780607 | 0.83 | ADAMTS4 (0.54) | HTTMAPTRAB9ANPC1KMT2A | |
| SCHEMBL21814531 | 0.81 | HTT (0.49) | HTTMAPTRAB9ANPC1MMP2 | |
| SCHEMBL21814588 | 0.81 | HTT (0.49) | HTTMAPTRAB9ANPC1MMP2 | |
| P-Nitrophenol SCHEMBL7776372 | 0.79 | MMP9 (0.57) | HTTMAPTRAB9ANPC1KMT2A | |
| SCHEMBL22492652 | 0.77 | MMP2 (0.68) | HTTKMT2AMMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5193258 | 0.77 | MMP2 (0.68) | HTTKMT2AMMP2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464388-A1 | Detection assays having chromogenic and nonchromogenic, hypocromogenic, bathochromogenic or hypsochromogenic substrates | TECHNICON INSTRUMENTS CORPORATION (a New York corporation) (US) | 1992-01-08 | — | — | EP | disclosed |