Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776582 | 0.79 | SLC28A1 (0.42) | SLC29A1 | |
| SCHEMBL28199168 | 0.77 | PDE3A (0.42) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL28294920 | 0.77 | L3MBTL1 (0.36) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL5491556 | 0.76 | LMNA (0.52) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL28293060 | 0.76 | ADORA3 (0.42) | LMNASMN1; SMN2ALDH1A1NT5ETSHR | |
| SCHEMBL1896532 | 0.76 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL158512 | 0.75 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL27848944 | 0.75 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL19506976 | 0.75 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL12658357 | 0.75 | LMNA (0.51) | LMNAMTORTHRBMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473526-A | Process for producing oligonucleotide and nucleoside, nucleotide or oligonucleotide | 味之素株式会社 | 2018-08-31 | — | — | CN | disclosed |
| EP-0423839-B1 | Polynucleotides and probes useful in solution phase nucleic acid sandwich assay | BAYER AG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0225807-B1 | Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein | CHIRON CORP (US) | 1994-10-19 | — | — | EP | disclosed |