SCHEMBL7776582

SCHEMBL7776582

C[SiH](C)[C@@]1(n2ccc(=O)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.42
SLC28A2 O43868 1/20 0.42
SLC29A1 Q99808 1/20 0.42
SLC28A3 Q9HAS3 1/20 0.42
P2RY14 Q15391 5/20 0.36
P2RY2 P41231 5/20 0.35
P2RY4 P51582 3/20 0.35
P2RY6 Q15077 8/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28252054 0.88 SLC28A1 (0.46) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL5705604 0.87 SLC28A1 (0.39) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL3476782 0.84 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL8744204 0.82 TK1 (0.40)
SCHEMBL16267750 0.81 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL7776536 0.79 LMNA (0.44) SLC29A1
SCHEMBL8642269 0.78 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL9218584 0.77 P2RY2 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL26664353 0.77 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14
SCHEMBL992569 0.76 SLC28A1 (0.34) SLC28A1SLC28A2SLC29A1SLC28A3P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0423839-B1 Polynucleotides and probes useful in solution phase nucleic acid sandwich assay BAYER AG (US) 2001-08-16 EP disclosed
EP-0225807-B1 Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein CHIRON CORP (US) 1994-10-19 EP disclosed