Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910688 | 0.84 | LMNA (0.47) | LMNACYP1A2SMN1; SMN2TSHRNPSR1 | |
| SCHEMBL10618588 | 0.81 | CYP2C9 (0.40) | LMNASMN1; SMN2NPSR1HTT | |
| SCHEMBL3636157 | 0.81 | POLB (0.34) | LMNAPIK3CA | |
| SCHEMBL7978560 | 0.79 | NPSR1 (0.52) | LMNASMN1; SMN2TSHRNPSR1HPGD | |
| SCHEMBL2909014 | 0.79 | RAB9A (0.46) | LMNACYP1A2SMN1; SMN2TSHRNPSR1 | |
| SCHEMBL3298153 | 0.77 | POLB (0.52) | LMNACYP1A2RAB9AKDM4EALDH1A1 | |
| SCHEMBL7772250 | 0.75 | RAB9A (0.49) | LMNACYP1A2SMN1; SMN2TSHRHPGD | |
| SCHEMBL7772254 | 0.75 | TUBB4A (0.39) | LMNACYP1A2SMN1; SMN2TSHRHPGD | |
| SCHEMBL1677779 | 0.75 | CYP1A2 (0.43) | LMNACYP1A2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL3025720 | 0.75 | CYP1A2 (0.38) | LMNACYP1A2TSHRNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129081-A1 | PREPARATION OF TRIS-SUBSTITUTED ALKOXYCARBONYLAMINO-1,3,5-TRIAZINE COMPOUNDS | CYTEC TECHNOLOGY CORP. (US) | 2001-09-05 | — | — | EP | disclosed |
| US-6121446-A | Preparation of tris-substituted alkoxycarbonylamino-1,3,5-triazine compounds | CYTEC TECHNOLOGY CORPORATION | 2000-09-19 | — | — | US | disclosed |
| WO-2000027829-A1 | PREPARATION OF TRIS-SUBSTITUTED ALKOXYCARBONYLAMINO-1,3,5-TRIAZINE COMPOUNDS | CYTEC TECHNOLOGY CORP. (US) | 2000-05-18 | — | — | WO | disclosed |