Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 6/20 | 0.59 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.59 |
| ▸ | PARP1 | P09874 | 5/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.59 |
| ▸ | WNT3A | P56704 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108597 | 0.84 | RNASEL (0.51) | TNKSTNKS2PARP1PARP2WNT3A | |
| SCHEMBL14613050 | 0.81 | BRD4 (0.53) | TNKSTNKS2PARP1PARP2WNT3A | |
| SCHEMBL4738751 | 0.80 | ALDH1A1 (0.53) | TNKSTNKS2PARP1PARP2WNT3A | |
| SCHEMBL14612916 | 0.77 | PARP1 (0.43) | TNKSTNKS2PARP1PARP2WNT3A | |
| SCHEMBL7783581 | 0.77 | TNKS2 (0.70) | TNKSTNKS2PARP1PARP2WNT3A | |
| SCHEMBL1033822 | 0.74 | TNKS2 (0.55) | TNKSTNKS2PARP1PARP2WNT3A | |
| SCHEMBL9070566 | 0.72 | TNKS (0.63) | TNKSTNKS2PARP1WNT3AALDH1A1 | |
| SCHEMBL1032502 | 0.72 | TNKS2 (0.68) | TNKSTNKS2PARP1WNT3AALDH1A1 | |
| SCHEMBL7782104 | 0.70 | PARP1 (0.56) | TNKSTNKS2PARP1PARP2WNT3A | |
| SCHEMBL12634730 | 0.70 | TNKS (0.44) | TNKSTNKS2PARP1PARP2WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |