Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | NPY4R | P50391 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419869 | 0.90 | PLA2G2C (0.55) | NOD1PLA2G10PLA2G2CFAAH | |
| SCHEMBL30496630 | 0.86 | NOD2 (0.44) | NOD1NOD2SIRT5MMP2MMP8 | |
| SCHEMBL7772354 | 0.86 | PLA2G2C (0.51) | NOD1PLA2G10PLA2G2CFAAHESR1 | |
| SCHEMBL9437409 | 0.82 | NOD1 (0.44) | NOD1NOD2SIRT5ERAP2ERAP1 | |
| SCHEMBL11596384 | 0.82 | NOD2 (0.49) | NOD1NOD2SIRT5ERAP2ERAP1 | |
| SCHEMBL14598253 | 0.81 | NPY4R (0.48) | NOD1PLA2G10NOD2SIRT5NPY5R | |
| SCHEMBL14598251 | 0.81 | NPY4R (0.48) | NOD1PLA2G10NOD2SIRT5NPY5R | |
| SCHEMBL26842938 | 0.81 | CTSL (0.47) | NOD1PLA2G10PLA2G2CFAAH | |
| SCHEMBL11284359 | 0.80 | FAAH (0.50) | NOD1PLA2G10PLA2G2CFAAHESR1 | |
| SCHEMBL19724151 | 0.80 | NOD1 (0.49) | NOD1PLA2G10PLA2G2CMMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477912-B1 | Novel N-acyldipeptides, and pharmaceutical compositions containing the same | UNIV LJUBLJANI (SI) | 2001-08-29 | — | — | EP | claimed |
| US-5514654-A | ANTITUMOR AGENTS AND IMMUNOMODULATORS | UNIV LJUBLJANI (SI) | 1996-05-07 | — | — | US | claimed |
| EP-0477912-B1 | Novel N-acyldipeptides, and pharmaceutical compositions containing the same | UNIV LJUBLJANI (SI) | 2001-08-29 | — | — | EP | disclosed |
| US-5514654-A | ANTITUMOR AGENTS AND IMMUNOMODULATORS | UNIV LJUBLJANI (SI) | 1996-05-07 | — | — | US | disclosed |
| EP-0477912-A2 | Novel N-acyldipeptides, processes for the preparation thereof and pharmaceutical compositions containing the same | UNIVERZA EDVARDA KARDELJA V LJUBLJANI, VDO FAKULTETA ZA NARAVOSLOVJE IN TEHNOLOGIJO, N.SOL.O., LUBLJANA (YU) | 1992-04-01 | — | — | EP | disclosed |