Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785606 | 0.75 | ALDH1A1 (0.60) | ALDH1A1ALOX15MAPTRAB9AMAPK1 | |
| SCHEMBL466086 | 0.75 | ALDH1A1 (1.00) | ALDH1A1ALOX15MAPTRAB9AMAPK1 | |
| SCHEMBL1194406 | 0.75 | ALDH1A1 (1.00) | ALDH1A1ALOX15MAPTRAB9AMAPK1 | |
| SCHEMBL7774235 | 0.75 | ALDH1A1 (0.42) | ALDH1A1ALOX15MAPTMAPK1HPGD | |
| SCHEMBL9016538 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2KDM4ETDP1 | |
| SCHEMBL7831180 | 0.73 | CYP2A6 (0.38) | ALDH1A1ALOX15MAP2K1LIMK1 | |
| SCHEMBL1374464 | 0.72 | ALDH1A1 (0.69) | ALDH1A1ALOX15MAPTRAB9AMAPK1 | |
| SCHEMBL7769678 | 0.71 | MAPK1 (0.50) | ALDH1A1ALOX15MAPTRAB9AMAPK1 | |
| SCHEMBL7774394 | 0.71 | MAPT (0.43) | MAPTHSD17B10KDM4EG6PD | |
| SCHEMBL9578460 | 0.71 | ALDH1A1 (0.59) | ALDH1A1ALOX15MAPTRAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294527-B1 | ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0949262-B1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KK (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-1090920-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-04-11 | — | — | EP | disclosed |
| EP-0949262-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |