Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PHOSPHO1 | Q8TCT1 | 3/20 | 0.35 |
| ▸ | MPI | P34949 | 2/20 | 0.35 |
| ▸ | PMM2 | O15305 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016538 | 0.77 | ALDH1A1 (0.44) | MAPTKDM4EG6PDMIFPHOSPHO1 | |
| SCHEMBL7777262 | 0.76 | MAPT (0.43) | MAPTHSD17B10KDM4EG6PDTLR9 | |
| SCHEMBL7774411 | 0.70 | PARP1 (0.36) | HSD17B10CA12CA9MIFPARP1 | |
| SCHEMBL11560464 | 0.69 | EPHX2 (0.46) | HSD17B10KDM4EG6PDTLR9EPHX2 | |
| SCHEMBL28124653 | 0.68 | GPR3 (0.54) | MAPTG6PDTLR9EPHX2SCN4A | |
| SCHEMBL17341211 | 0.67 | EPHX2 (0.41) | MAPTHSD17B10EPHX2SCN4APPARA | |
| SCHEMBL16421246 | 0.66 | G6PD (0.47) | MAPTHSD17B10KDM4EG6PDTLR9 | |
| SCHEMBL17782899 | 0.66 | MAPT (0.61) | MAPTHSD17B10KDM4EG6PDTLR9 | |
| SCHEMBL121465 | 0.65 | BCKDK (0.48) | HSD17B10KDM4EG6PDTLR9PPARA | |
| SCHEMBL3627055 | 0.65 | CYP2C9 (0.45) | HSD17B10KDM4EPPARADYRK1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294527-B1 | ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0949262-B1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KK (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-0949262-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |