Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9016538 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTHTTMIFKDM4E | |
| SCHEMBL7774411 | 0.77 | PARP1 (0.36) | ALDH1A1ALOX15CA2MIFPARP1 | |
| SCHEMBL7777304 | 0.75 | ALDH1A1 (0.60) | ALDH1A1ALOX15HPGDMAOAMAOB | |
| SCHEMBL15003270 | 0.74 | MAOA (0.49) | ALDH1A1HPGDMAOAMAOBCA2 | |
| SCHEMBL7769678 | 0.74 | MAPK1 (0.50) | ALDH1A1ALOX15HPGDMAOBMAPT | |
| SCHEMBL7774394 | 0.74 | MAPT (0.43) | MAPTMIFCYP3A4PARP1CYP2C9 | |
| SCHEMBL7774088 | 0.74 | ALDH1A1 (0.39) | ALDH1A1ALOX15HPGDMAOAMAOB | |
| SCHEMBL29980342 | 0.73 | HTT (0.44) | ALDH1A1ALOX15HPGDMAOAMAOB | |
| SCHEMBL3874783 | 0.73 | HTT (0.44) | ALDH1A1ALOX15HPGDMAOAMAOB | |
| SCHEMBL10369249 | 0.72 | ESR1 (0.55) | ALOX15CA2HTTCYP3A4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294527-B1 | ANTIBIOTICS FOR METHACILLIN RESISTANT BACTERIA | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-0949262-B1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KK (JP) | 2001-08-22 | — | — | EP | disclosed |
| EP-1090920-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-04-11 | — | — | EP | disclosed |
| EP-0949262-A1 | CEPHEM COMPOUNDS | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-10-13 | — | — | EP | disclosed |