Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 9/20 | 0.44 |
| ▸ | BCKDK | O14874 | 1/20 | 0.42 |
| ▸ | PHOSPHO1 | Q8TCT1 | 8/20 | 0.41 |
| ▸ | G6PD | P11413 | 4/20 | 0.41 |
| ▸ | MIF | P14174 | 4/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | PMM2 | O15305 | 5/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774394 | 0.77 | MAPT (0.43) | MAPTMPIPHOSPHO1G6PDMIF | |
| SCHEMBL7777304 | 0.75 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTPOLBG6PD | |
| SCHEMBL31344216 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTPOLBMPI | |
| SCHEMBL4514959 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTPOLBMPI | |
| SCHEMBL7769678 | 0.74 | MAPK1 (0.50) | ALDH1A1LMNAMAPTMPIMIF | |
| SCHEMBL7774018 | 0.74 | ALDH1A1 (0.41) | ALDH1A1LMNAMAPTPOLBMPI | |
| SCHEMBL7774411 | 0.74 | PARP1 (0.36) | ALDH1A1MIF | |
| SCHEMBL9016698 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTPOLBMPI | |
| SCHEMBL11574705 | 0.68 | KDM4E (0.47) | ALDH1A1LMNAMAPTPOLBMPI | |
| SCHEMBL31344125 | 0.67 | KDM4E (0.54) | ALDH1A1LMNAMAPTPOLBMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481441-B1 | Novel cephem compounds, their preparation processes and antibacterial agents | KYORIN SEIYAKU KK (JP) | 1996-12-11 | — | — | EP | disclosed |
| US-5244892-A | Pseudomonas | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0481441-A2 | Novel cephem compounds, their preparation processes and antibacterial agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |