Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | CDC25A | P30304 | 4/20 | 0.43 |
| ▸ | CDC25B | P30305 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140705 | 0.79 | MEN1 (0.47) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| Deoxylapachol SCHEMBL2682330 | 0.78 | MEN1 (0.54) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| SCHEMBL25609380 | 0.78 | DHODH (0.54) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| Phosphine SCHEMBL14764881 | 0.77 | MEN1 (0.46) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| SCHEMBL7912021 | 0.76 | PTPN1 (0.52) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| SCHEMBL5810776 | 0.75 | PARK7 (0.58) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| SCHEMBL30673380 | 0.73 | S100A4 (0.53) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| SCHEMBL128020 | 0.73 | S100A4 (0.53) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| SCHEMBL9685830 | 0.72 | PTPN1 (0.52) | MEN1KMT2ANSD2L3MBTL1PTPN1 | |
| SCHEMBL3275939 | 0.72 | PTPN1 (0.52) | MEN1KMT2ANSD2L3MBTL1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574906-B1 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO (JP) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000008495-A2 | ANTIPROLIFERATIVE NAPHTHOQUINONES, DERIVATIVES, COMPOSITIONS, AND USES THEREOF | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2000-02-17 | — | — | WO | disclosed |
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |
| US-5380724-A | Inhibitors of lipid peroxidation | GYOGYSZERKUTATO INTEZET KFT (HU) | 1995-01-10 | — | — | US | disclosed |
| EP-0574906-A2 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-12-22 | — | — | EP | disclosed |