Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GALK1 | P51570 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4480218 | 0.81 | SLC6A4 (0.36) | KDM1AALDH1A1SLC6A4DRD2IDO1 | |
| SCHEMBL10476854 | 0.76 | KDM1A (0.38) | KDM1AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2155195 | 0.75 | KDM1A (0.43) | KDM1AALDH1A1SLC6A4DRD2IDO1 | |
| SCHEMBL11614041 | 0.73 | KDM1A (0.38) | KDM1AALDH1A1CYP1A2SLC6A4DRD2 | |
| SCHEMBL7775994 | 0.73 | KDM1A (0.38) | KDM1AALDH1A1SLC6A4DRD2IDO1 | |
| SCHEMBL5248281 | 0.73 | KDM1A (0.38) | KDM1AALDH1A1CYP1A2SLC6A4DRD2 | |
| SCHEMBL8506986 | 0.72 | SLC6A4 (0.36) | KDM1AALDH1A1CYP1A2SLC6A4DRD2 | |
| SCHEMBL7999943 | 0.71 | KDM1A (0.39) | KDM1AALDH1A1CYP1A2SLC6A4DRD2 | |
| SCHEMBL20597643 | 0.70 | HSD11B1 (0.37) | KDM1AALDH1A1SLC6A4DRD2IDO1 | |
| SCHEMBL14931728 | 0.70 | IDO1 (0.36) | KDM1AALDH1A1SLC6A4DRD2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673944-B1 | Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances | CELANESE CHEM EUROPE GMBH (DE) | 2001-08-16 | — | — | EP | disclosed |
| US-5767317-A | Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |
| EP-0673944-A1 | Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |