SCHEMBL7777457

SCHEMBL7777457

CCOP(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
IDO1 P14902 2/20 0.41
HTR2A P28223 2/20 0.40
HTR2B P41595 2/20 0.40
HTR2C P28335 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.39
SIGMAR1 Q99720 1/20 0.39
ADRA2C P18825 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
DRD3 P35462 1/20 0.39
OPRK1 P41145 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
ALDH1A1 P00352 3/20 0.38
POLB P06746 1/20 0.38
MAOB P27338 2/20 0.38
GAA P10253 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30356626 0.77 ACHE (0.39) IDO1MAPTLMNATAAR1POLB
SCHEMBL7776013 0.77 ACHE (0.39) IDO1MAPTLMNATAAR1POLB
SCHEMBL30356619 0.76 ACHE (0.44) L3MBTL1IDO1MAPK1MAPTLMNA
SCHEMBL7167520 0.73 TSHR (0.52) IDO1HTR2AHTR2BHTR2CTSHR
SCHEMBL31413753 0.73 CYP3A4 (0.36) IDO1TSHRMAPTTAAR1ALDH1A1
SCHEMBL30775610 0.72 ACHE (0.35) IDO1LMNASLC6A4POLBKDM4E
SCHEMBL30356625 0.71 AGXT (0.38) ALDH1A1
SCHEMBL196443 0.71 CYP3A4 (0.39) L3MBTL1TSHRALDH1A1NPSR1
SCHEMBL20710756 0.70 L3MBTL1 (0.51) L3MBTL1IDO1MAPTLMNAALDH1A1
SCHEMBL3025058 0.70 CES2 (0.48) IDO1HTR2AHTR2BHTR2CTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673944-B1 Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances CELANESE CHEM EUROPE GMBH (DE) 2001-08-16 EP claimed
US-5767317-A Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed