Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356626 | 1.00 | ACHE (0.39) | ACHEIDO1AGXTLMNATAAR1 | |
| SCHEMBL30775610 | 0.95 | ACHE (0.35) | ACHEIDO1AGXTLMNAPTGS1 | |
| SCHEMBL8638207 | 0.87 | NFE2L2 (0.44) | LMNAPTGS1MAOBMAPTNFE2L2 | |
| SCHEMBL30356619 | 0.80 | ACHE (0.44) | ACHEIDO1LMNATAAR1MAPT | |
| SCHEMBL31413753 | 0.77 | CYP3A4 (0.36) | IDO1AGXTTAAR1FBP1MAPT | |
| SCHEMBL30775608 | 0.77 | L3MBTL1 (0.40) | LMNANFE2L2 | |
| SCHEMBL7777457 | 0.77 | L3MBTL1 (0.43) | IDO1LMNATAAR1MAOBMAPT | |
| SCHEMBL30356625 | 0.76 | AGXT (0.38) | AGXT | |
| SCHEMBL7778608 | 0.75 | TDP1 (0.36) | ACHEIDO1AGXTLMNAMAOB | |
| SCHEMBL196443 | 0.74 | CYP3A4 (0.39) | GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673944-B1 | Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances | CELANESE CHEM EUROPE GMBH (DE) | 2001-08-16 | — | — | EP | claimed |
| US-5767317-A | Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | claimed |
| US-5767317-A | Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |