SCHEMBL397689

SCHEMBL397689

C=C(C)C(=O)Nc1ccc(NS(=O)(=O)c2cccc3ccccc23)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.62
PGR P06401 1/20 0.55
HDAC1 Q13547 3/20 0.55
RORA P35398 1/20 0.54
RORC P51449 1/20 0.54
NR1H2 P55055 1/20 0.54
NR1H4 Q96RI1 1/20 0.54
HTT P42858 2/20 0.53
ALDH1A1 P00352 1/20 0.53
PFKFB3 Q16875 1/20 0.53
HCRTR1 O43613 1/20 0.51
BRD4 O60885 1/20 0.49
PTPN2 P17706 1/20 0.46
PTPN1 P18031 1/20 0.46
PTPN5 P54829 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
LMNA P02545 1/20 0.44
CYP17A1 P05093 1/20 0.44
PKLR P30613 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7777757 0.86 HTT (0.47) TSHRPGRHDAC1RORARORC
SCHEMBL3254721 0.81 PGR (0.62) TSHRPGRHDAC1RORARORC
SCHEMBL7785890 0.81 HCRTR1 (0.51) TSHRPGRHDAC1RORARORC
SCHEMBL9568728 0.81 TSHR (0.64) TSHRPGRHDAC1RORARORC
SCHEMBL28825370 0.81 TSHR (0.64) TSHRPGRHDAC1RORARORC
SCHEMBL396802 0.80 KMT2A (0.70) HTTALDH1A1MEN1KMT2ALMNA
SCHEMBL398489 0.80 SLC40A1 (0.52) HTTALDH1A1HCRTR1MEN1KMT2A
SCHEMBL397469 0.78 MEN1 (0.61) HDAC1ALDH1A1MEN1KMT2A
SCHEMBL16785737 0.78 TSHR (0.67) TSHRPGRHDAC1RORARORC
SCHEMBL3261087 0.78 TSHR (0.71) TSHRPGRHDAC1RORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US claimed
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
EP-1972440-B1 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM CORP (JP) 2010-06-23 EP disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
EP-1972440-A2 Negative lithographic printing plate precursor and lithographic printing method using the same FUJIFILM Corporation (JP) 2008-09-24 EP disclosed
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
EP-1077392-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2001-02-21 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0330239-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-22 EP disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed
US-5141838-A Lithography printing plates FUJI PHOTO FILM CO., LTD. (JP) 1992-08-25 US disclosed
EP-0330239-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1989-08-30 EP disclosed