SCHEMBL7784534

SCHEMBL7784534

C=C(C)C(=O)Oc1ccc(S(=O)(=O)NS(=O)(=O)c2cccc3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 1/20 0.44
ELANE P08246 2/20 0.44
PGR P06401 1/20 0.43
TSHR P16473 1/20 0.40
F2 P00734 2/20 0.40
PRSS1 P07477 2/20 0.40
PRSS2 P07478 2/20 0.40
PRSS3 P35030 2/20 0.40
ALDH1A1 P00352 2/20 0.39
GAA P10253 1/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
HTR6 P50406 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
NLRP3 Q96P20 1/20 0.38
PRTN3 P24158 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3254721 0.85 PGR (0.62) HCRTR1ELANEPGRTSHRALDH1A1
SCHEMBL7784393 0.83 L3MBTL1 (0.49) ELANEPGRF2PRSS1PRSS2
SCHEMBL3272714 0.82 KMT2A (0.59) ELANEALDH1A1GAAMEN1LMNA
SCHEMBL7777757 0.80 HTT (0.47) HCRTR1PGRTSHRF2PRSS1
SCHEMBL7784371 0.79 MMP2 (0.53) ELANEF2PRSS1PRSS2PRSS3
SCHEMBL7784467 0.79 ELANE (0.47) ELANEALDH1A1GAAMEN1LMNA
SCHEMBL14268209 0.77 KMT2A (0.48) ELANEGAALMNAHTTKMT2A
SCHEMBL7782606 0.76 LMNA (0.42) TSHRALDH1A1MEN1LMNAKMT2A
SCHEMBL27403633 0.75 ELANE (0.39) HCRTR1ELANEF2PRSS1PRSS2
SCHEMBL7782512 0.75 ELANE (0.47) ELANEPGRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed