Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784737 | 0.92 | MAOA (0.42) | MAOAMAOBKDM4EALDH1A1GAA | |
| SCHEMBL7785839 | 0.92 | MAOA (0.36) | MAOAMAOBKDM4EALDH1A1GAA | |
| SCHEMBL7784793 | 0.87 | KDM4E (0.44) | MAOAMAOBKDM4EALDH1A1GAA | |
| SCHEMBL7783639 | 0.83 | VCAM1 (0.39) | MAOAMAOBKDM4EALDH1A1GAA | |
| SCHEMBL7782990 | 0.80 | AKR1B1 (0.32) | MAOAMAOBKDM4EALDH1A1PTGDR2 | |
| SCHEMBL7778321 | 0.77 | PTGDR2 (0.35) | KDM4EALDH1A1GAAPTGDR2HPGD | |
| SCHEMBL7782879 | 0.75 | APEX1 (0.38) | KDM4EALDH1A1GAACNR1MEN1 | |
| SCHEMBL7784777 | 0.75 | KDM4E (0.33) | KDM4EALDH1A1GAACNR1HPGD | |
| SCHEMBL8532395 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1GAACNR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL28752946 | 0.72 | KDM4E (0.37) | KDM4EALDH1A1GAACNR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |