Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784740 | 0.92 | PTGDR2 (0.36) | PTGDR2AKR1B1RXFP1KDM4EMEN1 | |
| SCHEMBL9015141 | 0.84 | RXFP1 (0.35) | RXFP1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL7782990 | 0.80 | AKR1B1 (0.32) | PTGDR2AKR1B1RXFP1KDM4EMEN1 | |
| SCHEMBL5812558 | 0.80 | RXFP1 (0.36) | RXFP1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL5812554 | 0.79 | CTSS (0.34) | RXFP1MEN1LMNAHPGDKMT2A | |
| SCHEMBL9015078 | 0.79 | KDM4E (0.37) | RXFP1KDM4EMEN1ALDH1A1LMNA | |
| Chlorfenapyr SCHEMBL40337 | 0.78 | RXFP1 (0.35) | RXFP1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL5819704 | 0.77 | CTSS (0.33) | RXFP1MEN1HPGDKMT2A | |
| SCHEMBL7777931 | 0.77 | MAOA (0.38) | PTGDR2AKR1B1KDM4EMEN1ALDH1A1 | |
| SCHEMBL7784930 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |