Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782866 | 0.92 | NPSR1 (0.35) | AKR1B1PTGDR2NPSR1MEN1KMT2A | |
| SCHEMBL7783612 | 0.83 | MAPK1 (0.37) | AKR1B1PTGDR2NPSR1TDP1L3MBTL1 | |
| SCHEMBL7778321 | 0.80 | PTGDR2 (0.35) | AKR1B1PTGDR2MEN1KMT2ARXFP1 | |
| SCHEMBL7777931 | 0.80 | MAOA (0.38) | AKR1B1PTGDR2MEN1KMT2ATDP1 | |
| SCHEMBL678557 | 0.78 | KMT2A (0.41) | NPSR1MEN1KMT2ARXFP1MAPT | |
| SCHEMBL27810755 | 0.75 | GRIA2 (0.34) | NPSR1MEN1KMT2ARXFP1KDM4E | |
| Chlorfenapyr SCHEMBL40337 | 0.74 | RXFP1 (0.35) | MEN1KMT2ARXFP1MAPTKDM4E | |
| SCHEMBL5819704 | 0.73 | CTSS (0.33) | NPSR1MEN1KMT2ARXFP1HPGD | |
| Chlorfenapyr SCHEMBL28530561 | 0.73 | RXFP1 (0.35) | MEN1KMT2ARXFP1MAPTKDM4E | |
| Chlorfenapyr SCHEMBL27488880 | 0.73 | RXFP1 (0.35) | MEN1KMT2ARXFP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |