SCHEMBL7777984

SCHEMBL7777984

Cc1cn([C@H]2C[C@H](OS(=O)(=O)CC(C)c3ccccc3[N+](=O)[O-])[C@@H](CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.55
TK1 P04183 5/20 0.46
TK2 O00142 3/20 0.46
LMNA P02545 2/20 0.45
TSHR P16473 2/20 0.45
ALB P02768 1/20 0.45
PKM P14618 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782708 0.92 RNASE1 (0.46) RNASE1TK1TK2
SCHEMBL6573680 0.85 RNASE1 (0.59) RNASE1TK1TK2ALBPKM
SCHEMBL6572381 0.85 RNASE1 (0.59) RNASE1TK1TK2ALBPKM
SCHEMBL7777997 0.85 POLB (0.48)
SCHEMBL8072458 0.85 POLB (0.48)
SCHEMBL7777987 0.83 TK2 (0.43) RNASE1TK2
SCHEMBL21545799 0.81 RNASE1 (0.61) RNASE1TK1TK2LMNATSHR
SCHEMBL21563859 0.81 RNASE1 (0.61) RNASE1TK1TK2LMNATSHR
SCHEMBL7644968 0.80 RNASE1 (0.59) RNASE1TK1TK2
SCHEMBL8719327 0.80 RNASE1 (0.59) RNASE1TK1TK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901501-B1 NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS PFLEIDERER WOLFGANG (DE) 2001-10-17 EP disclosed