Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 2/20 | 0.43 |
| ▸ | TYMP | P19971 | 5/20 | 0.40 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777999 | 0.87 | P2RY6 (0.39) | TK2PYGM | |
| SCHEMBL7644575 | 0.85 | TK2 (0.45) | TK2TYMPRNASE1PYGM | |
| SCHEMBL7777984 | 0.83 | RNASE1 (0.55) | TK2RNASE1 | |
| SCHEMBL7644973 | 0.80 | TK2 (0.44) | TK2TYMPRNASE1PYGM | |
| SCHEMBL7644542 | 0.80 | TK2 (0.45) | TK2TYMPRNASE1 | |
| SCHEMBL6891122 | 0.78 | P2RY6 (0.38) | — | |
| SCHEMBL6891984 | 0.78 | DNPH1 (0.38) | TK2 | |
| SCHEMBL8072458 | 0.78 | POLB (0.48) | — | |
| SCHEMBL7777997 | 0.78 | POLB (0.48) | — | |
| SCHEMBL2585241 | 0.77 | TK2 (0.55) | TK2TYMPPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901501-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 2001-10-17 | — | — | EP | disclosed |