Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.36 |
| ▸ | HTR6 | P50406 | 5/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782862 | 0.89 | ALDH1A1 (0.40) | PTGS2PTGS1KCNQ3KCNQ2PSD | |
| SCHEMBL7783642 | 0.83 | ALDH1A1 (0.39) | PTGS2KCNQ3KCNQ2PSD | |
| SCHEMBL7784695 | 0.73 | ALDH1A1 (0.41) | PTGS2KCNQ3KCNQ2PSD | |
| SCHEMBL7786266 | 0.72 | TYMS (0.36) | PSD | |
| SCHEMBL7784933 | 0.72 | GRM5 (0.39) | GRM5PTGS2PTGS1 | |
| SCHEMBL7782898 | 0.71 | PSD (0.41) | PTGS2KCNQ3KCNQ2PSD | |
| SCHEMBL8798414 | 0.69 | PSD (0.34) | KCNQ3KCNQ2PSD | |
| SCHEMBL7784898 | 0.68 | MEN1 (0.41) | GRM5PTGS2PTGS1FLT1FLT4 | |
| SCHEMBL7782970 | 0.66 | ALDH1A1 (0.43) | PTGS2HTR6 | |
| SCHEMBL8798325 | 0.66 | PSD (0.34) | KCNQ3KCNQ2PSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | claimed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |