Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783642 | 0.94 | ALDH1A1 (0.39) | ALDH1A1PTGS2CYP2C19KDM4EGAA | |
| SCHEMBL7778178 | 0.89 | GRM5 (0.39) | PTGS2PTGS1KCNQ3KCNQ2PSD | |
| SCHEMBL7782898 | 0.80 | PSD (0.41) | ALDH1A1CYP3A4MAPK1PTGS2CYP2C19 | |
| SCHEMBL8798414 | 0.75 | PSD (0.34) | ALDH1A1CYP2C19KDM4EGAAHPGD | |
| SCHEMBL7782970 | 0.75 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPK1PTGS2CYP2C19 | |
| SCHEMBL8798325 | 0.72 | PSD (0.34) | ALDH1A1CYP2C19KDM4EGAAHPGD | |
| SCHEMBL13858869 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAHPGDPSD | |
| SCHEMBL1180312 | 0.70 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL8662105 | 0.70 | PSD (0.34) | CYP2C19KDM4EKCNQ3KCNQ2PSD | |
| SCHEMBL7784739 | 0.70 | ALDH1A1 (0.43) | ALDH1A1CYP3A4MAPK1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | claimed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |