Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782901 | 0.88 | ALDH1A1 (0.40) | IDO1PTGS2PTGS1MEN1ALDH1A1 | |
| SCHEMBL7778327 | 0.80 | CA12 (0.40) | MEN1ALDH1A1KMT2ALMNAGLA | |
| SCHEMBL7784898 | 0.76 | MEN1 (0.41) | GRM5IDO1PTGS2PTGS1MEN1 | |
| SCHEMBL7778178 | 0.72 | GRM5 (0.39) | GRM5PTGS2PTGS1 | |
| SCHEMBL9228244 | 0.71 | ALDH1A1 (0.40) | GRM5IDO1MEN1ALDH1A1KMT2A | |
| SCHEMBL1180120 | 0.70 | DYRK1A (0.43) | GRM5IDO1MEN1ALDH1A1KMT2A | |
| SCHEMBL7784695 | 0.70 | ALDH1A1 (0.41) | IDO1PTGS2MEN1ALDH1A1KMT2A | |
| SCHEMBL9518605 | 0.69 | DYRK1A (0.39) | GRM5IDO1MEN1ALDH1A1KMT2A | |
| SCHEMBL9224754 | 0.67 | VCAM1 (0.37) | GRM5IDO1MEN1ALDH1A1KMT2A | |
| SCHEMBL12313417 | 0.67 | MAPT (0.43) | GRM5IDO1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |