Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782889 | 0.90 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AACLYPTGS2 | |
| SCHEMBL7786289 | 0.89 | ALDH1A1 (0.50) | MEN1ALDH1A1KMT2APTGS2PTGS1 | |
| SCHEMBL7784857 | 0.80 | MEN1 (0.43) | MEN1ALDH1A1KMT2AMCL1FLT1 | |
| SCHEMBL8662561 | 0.76 | ALDH1A1 (0.40) | MEN1ALDH1A1KMT2AMCL1 | |
| SCHEMBL7784933 | 0.76 | GRM5 (0.39) | MEN1ALDH1A1KMT2AGRM5ACLY | |
| SCHEMBL7784410 | 0.71 | MAOA (0.43) | MEN1ALDH1A1KMT2AMCL1IDO1 | |
| SCHEMBL7786310 | 0.69 | GRM5 (0.35) | MEN1ALDH1A1KMT2AGRM5ACLY | |
| SCHEMBL9221279 | 0.68 | MCL1 (0.46) | MEN1ALDH1A1KMT2AMCL1MET | |
| SCHEMBL7778178 | 0.68 | GRM5 (0.39) | GRM5PTGS2PTGS1FLT1FLT4 | |
| SCHEMBL9219554 | 0.67 | MCL1 (0.45) | MEN1ALDH1A1KMT2APTGS2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |