Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773780 | 0.86 | POLB (0.34) | POLBLMNAKDM4E | |
| SCHEMBL7780726 | 0.85 | POLB (0.38) | POLBHTR4CHRM4CHRM5ADRA2C | |
| SCHEMBL7338684 | 0.84 | AVPR2 (0.38) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7778566 | 0.83 | AVPR2 (0.38) | MEN1KMT2A | |
| SCHEMBL7348135 | 0.82 | FDPS (0.39) | KDM4E | |
| SCHEMBL7340038 | 0.81 | L3MBTL3 (0.43) | POLBHSD11B1L3MBTL3LRRK2TLR9 | |
| SCHEMBL7337645 | 0.80 | ALDH1A1 (0.40) | POLBKMT2A | |
| SCHEMBL7343093 | 0.77 | POLB (0.39) | POLBCHRM4CHRM5CHRM3L3MBTL3 | |
| SCHEMBL7338964 | 0.75 | KMT2A (0.43) | POLBHTR4MEN1KMT2AKDM4E | |
| SCHEMBL7375025 | 0.74 | HTR1A (0.40) | POLBHTR4HTR1DADRA1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |