Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782901 | 0.91 | ALDH1A1 (0.40) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL7784933 | 0.80 | GRM5 (0.39) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL10591135 | 0.78 | MMP2 (0.41) | MAPTMEN1KMT2AMCL1NPC1 | |
| SCHEMBL9224754 | 0.77 | VCAM1 (0.37) | MAPTMEN1KMT2AMCL1NPC1 | |
| SCHEMBL7784857 | 0.75 | MEN1 (0.43) | CA12CA1CA2CA9PTPN1 | |
| SCHEMBL9518605 | 0.72 | DYRK1A (0.39) | MAPTMEN1KMT2AMCL1POLB | |
| SCHEMBL10589530 | 0.72 | VCAM1 (0.42) | MAPTMEN1KMT2AMCL1NPC1 | |
| SCHEMBL9228244 | 0.71 | ALDH1A1 (0.40) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL1180120 | 0.70 | DYRK1A (0.43) | MAPTMEN1KMT2AMCL1POLB | |
| SCHEMBL1149000 | 0.70 | ALDH1A1 (0.67) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |