Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 16/20 | 0.50 |
| ▸ | HTR1B | P28222 | 14/20 | 0.50 |
| ▸ | HTR1F | P30939 | 10/20 | 0.50 |
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.50 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586357 | 0.88 | HTR1F (0.53) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8653413 | 0.87 | HTR1F (0.54) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8584756 | 0.85 | HTR1D (0.51) | HTR1DHTR1BHTR1FHTR1AQDPR | |
| SCHEMBL8584939 | 0.84 | HTR1D (0.37) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8613872 | 0.82 | SIGMAR1 (0.48) | HTR2A | |
| SCHEMBL8586456 | 0.81 | HTR1D (0.52) | HTR1DHTR1BHTR1FHTR1AQDPR | |
| SCHEMBL8586100 | 0.79 | HTR1D (0.41) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8586359 | 0.79 | HTR1F (0.53) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8586094 | 0.78 | HTR1D (0.40) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8636423 | 0.78 | HTR1F (0.54) | HTR1DHTR1BHTR1FHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001503774-A | — | — | 2001-03-21 | — | — | JP | claimed |
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | claimed |