Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435358 | 0.85 | KMT2A (0.54) | HTTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL6274755 | 0.82 | KMT2A (0.69) | HTTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8879807 | 0.81 | KDM4E (1.00) | HTTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL6880359 | 0.79 | KDM4E (0.45) | HTTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL7702205 | 0.78 | ALDH1A1 (0.59) | HTTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL28334704 | 0.76 | KDM4E (0.68) | HTTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL16365921 | 0.75 | KDM4E (0.76) | HTTKDM4EKMT2AMEN1HPGD | |
| SCHEMBL13873443 | 0.74 | HTT (0.66) | HTTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL8655345 | 0.74 | KDM4E (0.66) | HTTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL9260496 | 0.74 | KDM4E (0.56) | HTTKDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |