Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008232 | 0.92 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2AAVPR2AVPR1A | |
| SCHEMBL7335554 | 0.87 | ALDH1A1 (0.45) | ALDH1A1POLBKMT2AAVPR2AVPR1A | |
| SCHEMBL7339504 | 0.85 | AVPR2 (0.43) | ALDH1A1POLBKMT2AAVPR2AVPR1A | |
| SCHEMBL7780668 | 0.85 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2AAVPR2AVPR1A | |
| SCHEMBL7780700 | 0.85 | AVPR2 (0.48) | ALDH1A1POLBKMT2AAVPR2AVPR1A | |
| SCHEMBL8611049 | 0.83 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2AAVPR2AVPR1A | |
| SCHEMBL7476168 | 0.82 | MAP3K7 (0.34) | ALDH1A1POLBAVPR2AVPR1AAVPR1B | |
| SCHEMBL7338937 | 0.81 | KMT2A (0.44) | ALDH1A1POLBKMT2AAVPR2AVPR1A | |
| SCHEMBL7376228 | 0.81 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2AAVPR2AVPR1A | |
| Hydrochloric Acid SCHEMBL7337716 | 0.81 | AVPR2 (0.44) | AVPR2AVPR1AAVPR1BBRPF1MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |